Improving antibiotic treatment for chronic infections
Official title: Strategies for improving the efficacy of combinatorial antibiotic therapy in chronic infections
Funded at Texas Tech University · NIH-10886104 · Data updated 2026-11-12
This study is looking for ways to make antibiotic treatments work better for people with long-lasting infections, like those in wounds or lungs, by understanding how bacteria change and resist medicine, so we can find smarter ways to help you heal.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Texas Tech University NIH-funded |
| Lab location | 1 site (Lubbock, United States) |
| Project start | July 11, 2023 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $365,565 |
| NIH project number | 5R01AI173686-02 |
| Project ID | NIH-10886104 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from chronic infections that are difficult to treat, particularly those with antibiotic-resistant bacteria.
✕Less likely to help
Patients with acute infections or those not experiencing chronic infections may not benefit from this research.
What this research studies
This research focuses on enhancing the effectiveness of combined antibiotic therapies for chronic infections, such as those affecting wounds and lungs. It aims to address the growing problem of antibiotic resistance by understanding how chronic infections evolve and how different bacteria interact within these infections. The approach involves studying the stressors that bacteria face in the body and how these contribute to their ability to resist treatment. By targeting these factors, the research seeks to develop better strategies for clearing persistent infections.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for chronic infections, reducing morbidity and mortality associated with these conditions.
How similar studies have gone: Previous research has shown promise in improving antibiotic therapies for chronic infections, but this approach specifically targeting polymicrobial interactions is relatively novel.
Where this research is happening
-
Texas Tech University
Lubbock, United States Active
Researchers
- Principal investigator: Wakeman, Catherine Ann — Texas Tech University
- Study coordinator: Wakeman, Catherine Ann
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.