Improving 3D printing technology for better protein analysis
Official title: Administrative Supplement for Equipment: 6-axis Positioner to Improve 3D Print Quality and Print Size
Funded at Brigham Young University · NIH-10801667 · Data updated 2026-11-12
This study is working on a new, smaller device to better understand how proteins change shape, which could help scientists discover new treatments for diseases related to proteins, ultimately benefiting patients like you.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham Young University NIH-funded |
| Lab location | 1 site (Provo, United States) |
| Project start | April 1, 2019 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $99,983 |
| NIH project number | 3R15GM132868-02S1 |
| Project ID | NIH-10801667 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals affected by protein misfolding disorders, particularly those with Alzheimer's disease.
✕Less likely to help
Patients with conditions unrelated to protein dynamics or those not affected by protein misfolding disorders may not receive direct benefits from this research.
What this research studies
This research focuses on enhancing the accuracy of thermodynamic data related to protein unfolding by miniaturizing an adiabatic scanning calorimeter (ASC). By utilizing advanced 3D printing techniques, the project aims to create microfluidic devices that can provide precise measurements of protein behavior during phase transitions. This innovative approach seeks to overcome limitations of existing calorimetry methods, ultimately facilitating faster discoveries in pharmacology and biological chemistry. Patients may benefit indirectly through improved understanding and treatment of diseases linked to protein dynamics.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for diseases related to protein misfolding, such as Alzheimer's.
How similar studies have gone: Other research has shown promise in using advanced calorimetry techniques for studying protein dynamics, indicating a potential for success in this novel approach.
Where this research is happening
-
Brigham Young University
Provo, United States Active
Researchers
- Principal investigator: Munro, Troy — Brigham Young University
- Study coordinator: Munro, Troy
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.