Improving 3D imaging of tissues using advanced light techniques
Official title: Quantitative phase imaging andcomputational specificity (Popescu)
Funded at University of Illinois at Urbana-Champaign · NIH-10910243 · Data updated 2026-11-12
This study is working on a new imaging system that uses advanced technology to take clear, detailed pictures of living tissues, like skin, without needing any dyes or labels, which could help doctors better understand and diagnose conditions like cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Illinois at Urbana-Champaign NIH-funded |
| Lab location | 1 site (Champaign, United States) |
| Project start | September 30, 2022 |
| Project end | June 20, 2027 |
| Funding year | 2024 |
| Award (this year) | $181,999 |
| NIH project number | 5P41EB031772-03 |
| Project ID | NIH-10910243 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals requiring advanced imaging for conditions affecting deep tissues, such as skin disorders or cancers.
✕Less likely to help
Patients with superficial conditions that do not require deep tissue imaging may not benefit from this research.
What this research studies
This research focuses on enhancing quantitative phase imaging (QPI) technology to enable detailed imaging of cells and tissues in living organisms. By utilizing advanced computational methods and deep learning, the project aims to develop a new endoscopic system that can capture high-resolution 3D images of thick tissue structures, such as skin collagen, without the need for labels or dyes. This innovative approach combines various imaging techniques to provide real-time, non-destructive insights into tissue morphology and dynamics, which could significantly improve diagnostic capabilities in areas like cancer prognosis.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and earlier diagnoses of diseases, particularly cancer, through improved imaging techniques.
How similar studies have gone: Other research has shown promise in using advanced imaging techniques for biomedical applications, indicating a strong potential for success in this novel approach.
Where this research is happening
-
University of Illinois at Urbana-Champaign
Champaign, United States Active
Researchers
- Principal investigator: Bhargava, Rohit — University of Illinois at Urbana-Champaign
- Study coordinator: Bhargava, Rohit
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.