Improved magnetically guided blockage therapy for a common liver cancer
Official title: Improved Magnetomotive Embolization for Hepatocellular Carcinoma
Funded at Unandup, LLC · NIH-11318520 · Data updated 2026-11-12
A new approach uses magnetic guidance to improve targeted blockage of blood vessels feeding liver cancer in adults who may be candidates for embolization.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Unandup, LLC NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | September 1, 2026 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $405,753 |
| NIH project number | 1R43CA310649-01 |
| Project ID | NIH-11318520 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with hepatocellular carcinoma who are eligible for catheter-directed embolization.
✕Less likely to help
Patients not suitable for embolization or without liver cancer-related disease may not benefit.
What this research studies
This project focuses on hepatocellular carcinoma, a common and serious liver cancer. It explores a magnetomotive embolization method that could be more precise in blocking tumor blood supply. Researchers plan to test how magnetic forces can guide embolic particles during catheter-directed treatment, aiming for consistent delivery and fewer side effects. The work is designed with translational potential to improve real-world care for patients with liver cancer.
Why it matters
Potential benefit: If successful, patients could receive more effective, safer embolization therapy with better tumor control.
How similar studies have gone: Previous embolization approaches show benefit but standardization is variable; this study explores a novel magnet-guided method.
Where this research is happening
-
Unandup, LLC
Saint Louis, United States Active
Researchers
- Principal investigator: Creighton, Francis Milton — Unandup, LLC
- Study coordinator: Creighton, Francis Milton
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.