Improved Cardiovascular MRI with Equilibrium Phase bT1RESS Angiography
Official title: Improved Cardiovascular MRI Using Equilibrium Phase bT1RESS MR Angiography
Funded at Endeavor Health Clinical Operations · NIH-11293328 · Data updated 2026-11-12
A new MRI technique aims to create high-quality heart and blood vessel images using a contrast agent for patients who can’t take the usual contrast.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Endeavor Health Clinical Operations NIH-funded |
| Lab location | 1 site (Evanston, United States) |
| Project start | July 15, 2026 |
| Project end | March 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $1,553,928 |
| NIH project number | 1R01HL178521-01A1 |
| Project ID | NIH-11293328 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults 21 years and older who require cardiovascular MR angiography and can undergo MRI with standard contrast agents.
✕Less likely to help
Patients who cannot undergo MRI or cannot receive any contrast agent would not benefit from this method.
What this research studies
This project builds on a previously described MRI method (bT1RESS) to generate high-quality equilibrium-phase angiograms of the cardiovascular system. It develops a 2D-accelerated, ECG-gated protocol that works with standard contrast agents and allows imaging tens of minutes after contrast administration. The approach could reduce the amount of contrast agent needed while preserving or improving image clarity for diagnosing vascular conditions. The work is conducted at ENDEAVOR HEALTH CLINICAL OPERATIONS under the leadership of Dr. Robert R. Edelman.
Why it matters
Potential benefit: If successful, patients could receive clearer cardiovascular images with less contrast, potentially lowering risk and improving diagnostic confidence.
How similar studies have gone: This builds on a prior demonstration of equilibrium-phase imaging; the approach is novel in applying it to the cardiovascular system with standard contrast.
Where this research is happening
-
Endeavor Health Clinical Operations
Evanston, United States Active
Researchers
- Principal investigator: Edelman, Robert R. — Endeavor Health Clinical Operations
- Study coordinator: Edelman, Robert R.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.