Impact of COVID-19 on kidney diseases
Covid-19 induced worsening of glomerular diseases
This study is looking at how COVID-19 can make kidney problems like FSGS and diabetic nephropathy worse, and it aims to find ways to help people with these conditions who get COVID-19 feel better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rush University Medical Center NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-11014462 on NIH RePORTER |
What this research studies
This research investigates how COVID-19 can worsen existing kidney conditions, specifically focal and segmental glomerulosclerosis (FSGS) and diabetic nephropathy (DN). By mimicking the cytokine storm associated with COVID-19 in animal models, the study aims to understand the effects on kidney function and explore potential treatments to mitigate these effects. The research will also evaluate the role of specific cytokines in exacerbating kidney injury during COVID-19 infection. Ultimately, the goal is to improve outcomes for patients with these kidney diseases who contract COVID-19.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with existing kidney conditions such as FSGS or diabetic nephropathy who have contracted COVID-19.
Not a fit: Patients without pre-existing kidney conditions or those who have not contracted COVID-19 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for patients with kidney diseases who are affected by COVID-19.
How similar studies have performed: Other research has shown that cytokine storms can significantly impact various health conditions, suggesting that this approach may yield valuable insights.
Where this research is happening
Chicago, United States
- Rush University Medical Center — Chicago, United States (Active)
Researchers
- Principal investigator: Mace, Camille Emilie Adeline — Rush University Medical Center
- Study coordinator: Mace, Camille Emilie Adeline
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.