NIH-funded research R01 grant

Impact of COVID-19 on kidney diseases

Official title: Covid-19 induced worsening of glomerular diseases

Funded at Rush University Medical Center · NIH-11014462 · Data updated 2026-11-12

This study is looking at how COVID-19 can make kidney problems like FSGS and diabetic nephropathy worse, and it aims to find ways to help people with these conditions who get COVID-19 feel better.

More COVID-19 research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRush University Medical Center
NIH-funded
Lab location1 site (Chicago, United States)
Project startMarch 15, 2023
Project endDecember 31, 2027
Funding year2025
Award (this year)$312,840
NIH project number5R01DK133330-03
Project IDNIH-11014462 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals with existing kidney conditions such as FSGS or diabetic nephropathy who have contracted COVID-19.

Less likely to help

Patients without pre-existing kidney conditions or those who have not contracted COVID-19 may not benefit from this research.

What this research studies

This research investigates how COVID-19 can worsen existing kidney conditions, specifically focal and segmental glomerulosclerosis (FSGS) and diabetic nephropathy (DN). By mimicking the cytokine storm associated with COVID-19 in animal models, the study aims to understand the effects on kidney function and explore potential treatments to mitigate these effects. The research will also evaluate the role of specific cytokines in exacerbating kidney injury during COVID-19 infection. Ultimately, the goal is to improve outcomes for patients with these kidney diseases who contract COVID-19.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies for patients with kidney diseases who are affected by COVID-19.

How similar studies have gone: Other research has shown that cytokine storms can significantly impact various health conditions, suggesting that this approach may yield valuable insights.

Where this research is happening

  • Rush University Medical Center
    Chicago, United States
    Active

Researchers

  • Principal investigator: Mace, Camille Emilie Adeline — Rush University Medical Center
  • Study coordinator: Mace, Camille Emilie Adeline

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.