Impact of a low nicotine standard on real-world tobacco use in New Zealand
Official title: Assessing the real-world impact of a low nicotine product standard for smoked tobacco in New Zealand
Funded at Wake Forest University Health Sciences · NIH-11455245 · Data updated 2026-11-12
A real-world study will follow adults who smoke to see how a mandated lower nicotine level across all smoked tobacco affects their smoking habits and health over several years.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wake Forest University Health Sciences NIH-funded |
| Lab location | 1 site (Winston-Salem, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $20,226 |
| NIH project number | 3R01DA058264-04S1 |
| Project ID | NIH-11455245 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults who currently smoke daily or nearly daily and are willing to participate in long-term follow-up and data collection.
✕Less likely to help
Individuals who do not smoke or who are unwilling to participate in long-term follow-up or provide medical records and biomarkers.
What this research studies
This study will enroll about 1,500 adults who smoke daily or almost daily and track them over 3.5 years. It uses online surveys, biomarker testing, physiological measures, interviews, and medical records to understand changes in smoking behavior, health, and well-being after a potential nicotine reduction policy. The approach aims to capture real-life responses to lower nicotine products beyond controlled trials, including long-term effects and personal experiences. The findings could inform policy decisions about how nicotine reduction might work in everyday settings.
Why it matters
Potential benefit: If successful, the study could guide policies that reduce smoking-related health risks and help people quit or cut back.
How similar studies have gone: Previous trials suggested reductions in use and exposure, but this study extends to real-world, longitudinal settings with diverse data sources.
Where this research is happening
-
Wake Forest University Health Sciences
Winston-Salem, United States Active
Researchers
- Principal investigator: Denlinger-Apte, Rachel — Wake Forest University Health Sciences
- Study coordinator: Denlinger-Apte, Rachel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.