NIH-funded research R01 grant

Imagining your future to support weight loss

Official title: Adapting Episodic Future Thinking for Behavioral Weight Loss: Comparing Strategies and Characterizing Treatment Response

Funded at Miriam Hospital · NIH-11168679 · Data updated 2026-11-12

This project compares two ways of using future-imagining exercises to help adults with overweight or obesity lose weight in an online behavioral program.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMiriam Hospital
NIH-funded
Lab location1 site (Providence, United States)
Project startSeptember 23, 2021
Project endAugust 31, 2027
Funding year2025
Award (this year)$570,515
NIH project number5R01DK128412-04
Project IDNIH-11168679 on NIH RePORTER

Who could benefit from this research

Could help

Adults with overweight or obesity who want to lose weight and are willing to participate in an online behavioral program are the best fit.

Less likely to help

People who need immediate medical or surgical weight-loss treatments, who cannot use internet-based programs, or who have uncontrolled psychiatric or cognitive conditions may not benefit from this approach.

What this research studies

You would join an internet-delivered behavioral weight-loss program and be randomly assigned to one of three options: the standard program, a PREVENT version that helps you imagine future negative consequences of unhealthy choices, or a PROMOTE version that helps you imagine positive future benefits of healthy choices. You would practice episodic future thinking exercises, track your weight and food choices online, and complete brief questionnaires about motivation and food reward. The researchers will measure weight change, eating behavior, and related cognitive measures over time and look for patterns that show who benefits most from each approach.

Why it matters

Potential benefit: If successful, this approach could help people lose more weight by shifting attention away from immediate food rewards toward future goals.

How similar studies have gone: Previous small trials and the investigators' pilot R03 showed that episodic future thinking can improve food choices and reduce intake, with the PREVENT approach showing promising weight loss versus standard care.

Where this research is happening

  • Miriam Hospital
    Providence, United States
    Active

Researchers

  • Principal investigator: Demos, Kathryn E — Miriam Hospital
  • Study coordinator: Demos, Kathryn E

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.