Imaging lung ventilation and blood flow using advanced MRI techniques
Official title: Dynamic Imaging of Lung Ventilation and Perfusion Using CT and MRI
Funded at University of Iowa · NIH-10913594 · Data updated 2026-11-12
This study is testing a new way to take detailed pictures of your lungs while you breathe normally, which could help doctors better understand and treat chronic lung diseases without using harmful radiation.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Iowa NIH-funded |
| Lab location | 1 site (Iowa City, United States) |
| Project start | September 1, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $698,866 |
| NIH project number | 5R01HL169765-02 |
| Project ID | NIH-10913594 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with chronic lung conditions such as asthma, cystic fibrosis, or bronchiectasis.
✕Less likely to help
Patients with acute respiratory conditions or those unable to undergo MRI due to contraindications may not benefit from this research.
What this research studies
This research focuses on developing a new imaging technique that uses oxygen-enhanced MRI to visualize lung ventilation and structure in real-time. The method allows for high-resolution imaging of lung anatomy while patients breathe freely, capturing both ventilation dynamics and lung structure in just seven minutes. By employing advanced motion compensation and deep learning techniques, the study aims to improve the accuracy of lung disease assessments without exposing patients to ionizing radiation. The research will evaluate its effectiveness in various chronic lung diseases, comparing it to existing imaging methods.
Why it matters
Potential benefit: If successful, this research could provide a safer and more accurate way to assess lung function and structure in patients with chronic lung diseases.
How similar studies have gone: Preliminary data suggests that similar imaging techniques have shown promise, indicating potential for success in this novel approach.
Where this research is happening
-
University of Iowa
Iowa City, United States Active
Researchers
- Principal investigator: Fain, Sean Bedilion — University of Iowa
- Study coordinator: Fain, Sean Bedilion
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.