Identifying risk factors for severe COVID-19-related inflammatory syndrome in children
Official title: Identification of Risk Factors for predicting outcomes of COVID-19-Related Multisystem Inflammatory Syndrome in Children (MISC) using Real World Clinical Data
Funded at Northwestern University at Chicago · NIH-10679093 · Data updated 2026-11-12
This study is looking at what makes some kids more likely to get sick with Multisystem Inflammatory Syndrome after having COVID-19, so we can find ways to help those who might need extra care.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University at Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | August 8, 2022 |
| Project end | July 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $199,562 |
| NIH project number | 5R21HD107571-02 |
| Project ID | NIH-10679093 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include children who have had COVID-19 and are at risk for developing MIS-C or have already been diagnosed with it.
✕Less likely to help
Patients who have not had COVID-19 or do not exhibit symptoms of MIS-C may not benefit from this research.
What this research studies
This research investigates the risk factors and biomarkers associated with Multisystem Inflammatory Syndrome in Children (MIS-C) that can occur after COVID-19 infection. By analyzing electronic health record data from multiple health systems in Chicago, the study aims to better understand the characteristics of MIS-C patients, including those who may require intensive care. The goal is to identify patterns that could help in predicting severe outcomes and guide treatment strategies for affected children.
Why it matters
Potential benefit: If successful, this research could lead to improved identification and management of children at risk for severe MIS-C, potentially reducing complications and improving outcomes.
How similar studies have gone: Previous research has shown promising results in understanding post-COVID inflammatory syndromes, but this specific approach leveraging large electronic health record data is relatively novel.
Where this research is happening
-
Northwestern University at Chicago
Chicago, United States Active
Researchers
- Principal investigator: Walunas, Theresa L — Northwestern University at Chicago
- Study coordinator: Walunas, Theresa L
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.