Identifying resistant bacteria to improve infection prevention in patients with weakened immune systems
Screening for Resistant Enteric Bacteria to Personalize Infection Prevention Strategies in Neutropenic Patients
This study is looking at patients with low white blood cell counts, who are more likely to get serious infections, to see how often they carry bacteria that resist antibiotics and how this might increase their chances of getting bloodstream infections, so we can improve ways to prevent these infections.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10656238 on NIH RePORTER |
What this research studies
This research focuses on neutropenic patients, who are at high risk for severe infections due to low white blood cell counts. It aims to determine how common it is for these patients to carry antibiotic-resistant bacteria and how this affects their risk of developing bloodstream infections. The study will use advanced diagnostic tests to quickly identify patients with these resistant bacteria, allowing for tailored infection prevention strategies. By understanding the relationship between gut bacteria and infection risk, the research seeks to enhance the effectiveness of current antibiotic prophylaxis treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are neutropenic patients, particularly those undergoing cancer treatment who are at risk for Gram-negative bloodstream infections.
Not a fit: Patients who are not neutropenic or those not undergoing treatments that compromise their immune system may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to personalized infection prevention strategies that significantly reduce the risk of severe infections in neutropenic patients.
How similar studies have performed: Other research has shown promising results in identifying antibiotic-resistant bacteria and tailoring treatment strategies, indicating that this approach has potential for success.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Satlin, Michael Joseph — Weill Medical Coll of Cornell Univ
- Study coordinator: Satlin, Michael Joseph
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.