Identifying pain response predictors for endoscopic treatment in chronic pancreatitis
Official title: Predictive Biosignature for Endoscopic Therapy for Chronic Pancreatitis Pain
Funded at New York University School of Medicine · NIH-10794609 · Data updated 2026-11-12
This study is looking to find out which patients with chronic pancreatitis are likely to benefit from special treatments to relieve their pain, using some cool techniques to understand both their physical and emotional experiences, so that doctors can provide more personalized care and help reduce the need for pain medications.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 22, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $1,244,812 |
| NIH project number | 1UG3NS135170-01 |
| Project ID | NIH-10794609 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from chronic pancreatitis, particularly those experiencing pain related to ductal obstruction.
✕Less likely to help
Patients without chronic pancreatitis or those whose pain is not related to ductal obstruction may not benefit from this research.
What this research studies
This research investigates how to predict which patients with chronic pancreatitis will respond to endoscopic therapies for pain relief. It utilizes advanced techniques such as electroencephalography (EEG) and quantitative sensory testing (QST) to assess both physical and psychological factors affecting pain. By combining these methods, the study aims to create a predictive biosignature that can help tailor treatments to individual patients, potentially reducing reliance on opioids and improving pain management outcomes.
Why it matters
Potential benefit: If successful, this research could lead to more effective pain management strategies for patients with chronic pancreatitis, reducing the need for opioids.
How similar studies have gone: Other research has shown promise in using multimodal approaches for pain prediction, suggesting that this method could be effective.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Doan, Lisa — New York University School of Medicine
- Study coordinator: Doan, Lisa
Related research
Other NIH-funded projects on the same topics.
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Chronic Pancreatitis and Related Conditions Data Center Supports Multi-Center Research
A national effort to organize and share clinical data and biosamples from people with chronic pancreatitis, pancreatogenic diabetes, and pancreatic cancer to speed biomarker discovery and new treatments.
-
Malabsorption Blood Test for Exocrine Pancreatic Function in Chronic Pancreatitis
A blood test (MBT) will help identify people with mild to moderate pancreatic fat malabsorption and show how well enzyme therapy improves their quality of life.
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Chronic Pancreatitis Clinical Research Cohort and Biorepository
A long-term study at UF/Advent Health following adults with acute, relapsing, and chronic pancreatitis to build a detailed group with biospecimens and data for better diagnosis and personalized care.
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Cedars-Sinai Center leads research on chronic pancreatitis and pancreatic cancer
A Cedars-Sinai research center is renewing its program to study chronic pancreatitis, diabetes-related pancreatic disease, and pancreatic cancer so doctors can better understand and treat these conditions.
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UPMC Center for Pancreatitis and Diabetes research program
A specialized center at the University of Pittsburgh is advancing clinical and biological studies of chronic pancreatitis, recurrent acute pancreatitis, and diabetes to improve understanding and care.
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Chronic Pancreatitis Research Network to Understand Symptoms and Find Treatments
This project advances studies of chronic pancreatitis to understand why some people progress and to test new ideas that could diagnose or slow the disease.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.