Identifying new risk factors and treatments for carotid artery narrowing
Leveraging the Genetics of carotid stenosis for identifying novel risk factors and therapeutic opportunities
This study is looking into how our genes might affect carotid stenosis, a condition that can increase the risk of strokes, to help find better ways to prevent and treat it for people with heart-related issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Philadelphia VA Medical Center NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10863814 on NIH RePORTER |
What this research studies
This research investigates the genetic factors associated with carotid stenosis, a condition that can lead to serious cardiovascular events like strokes. By analyzing data from the VA Million Veteran Program, the study aims to uncover specific biological markers and risk factors that contribute to this condition. The approach includes advanced techniques such as natural language processing to analyze large datasets, which may lead to more personalized prevention and treatment strategies for patients with atherosclerotic cardiovascular disease.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a history of carotid artery narrowing or those at risk for atherosclerotic cardiovascular disease.
Not a fit: Patients without any cardiovascular risk factors or those who do not have carotid artery diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved risk assessment and targeted therapies for patients at risk of carotid artery diseases.
How similar studies have performed: Previous genetic studies in related cardiovascular conditions have shown promising results, indicating that this approach could yield valuable insights.
Where this research is happening
Philadelphia, United States
- Philadelphia VA Medical Center — Philadelphia, United States (Active)
Researchers
- Principal investigator: Damrauer, Scott Michael — Philadelphia VA Medical Center
- Study coordinator: Damrauer, Scott Michael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.