Identifying new markers to improve treatment for children with asthma attacks

Novel Markers of Treatment Responsiveness for Pediatric Acute Asthma Exacerbations

['FUNDING_OTHER'] · UNIVERSITY OF COLORADO DENVER · NIH-10994056

This study is looking for new ways to help doctors treat kids having asthma attacks by finding special markers that show how well different treatments might work for each child, so they can get the best care possible and feel better faster.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF COLORADO DENVER (nih funded)
Locations1 site (Aurora, UNITED STATES)
Trial IDNIH-10994056 on ClinicalTrials.gov

What this research studies

This research focuses on improving the management of acute asthma exacerbations in children by identifying novel biological and physiological markers that can predict treatment responsiveness. Currently, treatments in emergency departments are standardized and may not be effective for all patients, leading to challenges in care. By utilizing advanced techniques like nasal transcriptome analysis and airway oscillometry, the study aims to develop a more personalized approach to treatment, ensuring that children receive the most effective therapies based on their individual responses. This could lead to better outcomes and reduced hospital stays for young patients experiencing asthma attacks.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 0-11 years who are experiencing acute asthma exacerbations.

Not a fit: Patients with chronic asthma who are not experiencing acute exacerbations may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and tailored treatments for children suffering from acute asthma exacerbations.

How similar studies have performed: While the approach of using novel biomarkers in asthma management is innovative, similar studies have shown promise in improving treatment outcomes in other respiratory conditions.

Where this research is happening

Aurora, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acute Respiratory Distress Syndrome, Adult Respiratory Distress Syndrome

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.