Identifying MIS-C in children with fever
Diagnosis of MIS-C in febrile children
This study is working on a new way to help doctors quickly identify multisystem inflammatory syndrome in children who have had COVID-19 by looking at changes in their breath, urine, and saliva, so that kids can get the right care faster.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10847804 on NIH RePORTER |
What this research studies
This research focuses on developing a new diagnostic tool to identify multisystem inflammatory syndrome in children (MIS-C) who have experienced COVID-19. It aims to analyze changes in breath, urine, and saliva from febrile children to find specific biomarkers associated with MIS-C. By integrating these findings with clinical and immunological data, the researchers hope to create a reliable method for distinguishing MIS-C from other febrile conditions. This could lead to faster and more accurate diagnoses for affected children.
Who could benefit from this research
Good fit: Ideal candidates for this research are children who have experienced fever and may have been infected with SARS-CoV-2.
Not a fit: Patients who do not exhibit fever or have not been exposed to COVID-19 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the diagnosis and management of MIS-C in children, leading to better health outcomes.
How similar studies have performed: Other research has shown promise in using biomarker analysis for diagnosing inflammatory conditions, suggesting potential success for this novel approach.
Where this research is happening
Philadelphia, United States
- Children's Hosp of Philadelphia — Philadelphia, United States (Active)
Researchers
- Principal investigator: Odom John, Audrey Ragan — Children's Hosp of Philadelphia
- Study coordinator: Odom John, Audrey Ragan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.