Identifying metabolic factors that influence outcomes in multiple sclerosis
Official title: Metabolic predictors of disease outcomes in multiple sclerosis
Funded at Johns Hopkins University · NIH-11036318 · Data updated 2026-11-12
This study is looking at how changes in your body's metabolism, especially with amino acids, might help predict how multiple sclerosis (MS) could progress, using blood samples from people with MS to find markers that show the risk of worsening symptoms, which could lead to more tailored treatments just for you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | February 15, 2024 |
| Project end | January 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $575,637 |
| NIH project number | 5R01NS133005-02 |
| Project ID | NIH-11036318 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with multiple sclerosis who are experiencing varying degrees of symptoms.
✕Less likely to help
Patients with other neurological disorders or those without a diagnosis of multiple sclerosis may not benefit from this research.
What this research studies
This research investigates how changes in metabolism, particularly related to amino acids, can predict the progression of multiple sclerosis (MS). By analyzing blood samples from individuals with MS, researchers aim to discover biomarkers that indicate the risk of worsening symptoms. The study utilizes advanced metabolomics technology to assess metabolic profiles and their correlation with disease severity. This approach could lead to more personalized treatment strategies for MS patients based on their unique metabolic characteristics.
Why it matters
Potential benefit: If successful, this research could enable more accurate predictions of disease progression in multiple sclerosis, leading to tailored treatment plans.
How similar studies have gone: Previous research has shown promising results in identifying metabolic changes in MS patients, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Fitzgerald, Kathryn C. — Johns Hopkins University
- Study coordinator: Fitzgerald, Kathryn C.
Related research
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-
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-
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Promoting brain repair in MS with a natural compound that nudges neural stem cells
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.