Identifying kidney-related risk factors for severe lung disease in premature infants
Official title: Improving the prediction of bronchopulmonary dysplasia by identifying kidney-based risk factors
Funded at Indiana University Indianapolis · NIH-10991668 · Data updated 2026-11-12
This study is looking at how kidney problems and too much fluid can lead to serious lung issues in premature babies, and it aims to help doctors spot which babies might be at risk so they can provide better care and improve their health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project start | December 1, 2023 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $182,416 |
| NIH project number | 5K23HL168362-02 |
| Project ID | NIH-10991668 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are premature infants born before 28 weeks of gestation who may be at risk for developing severe bronchopulmonary dysplasia.
✕Less likely to help
Patients who are not premature or do not have risk factors for bronchopulmonary dysplasia may not benefit from this research.
What this research studies
This research focuses on understanding how acute kidney injury and fluid overload affect the development of severe bronchopulmonary dysplasia (BPD) in premature infants. By identifying kidney-based risk factors, the study aims to create a clinical prediction model that can help healthcare providers identify at-risk infants early on. The approach involves analyzing data from premature infants to establish connections between kidney health and lung disease, ultimately leading to better-targeted interventions. The goal is to improve outcomes for these vulnerable infants by addressing preventable and treatable conditions.
Why it matters
Potential benefit: If successful, this research could lead to improved early detection and prevention strategies for severe bronchopulmonary dysplasia in premature infants.
How similar studies have gone: Other research has shown promising results in identifying risk factors for bronchopulmonary dysplasia, making this approach both relevant and potentially impactful.
Where this research is happening
-
Indiana University Indianapolis
Indianapolis, United States Active
Researchers
- Principal investigator: Starr, Michelle C — Indiana University Indianapolis
- Study coordinator: Starr, Michelle C
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.