Identifying kidney-related risk factors for severe lung disease in premature infants

Improving the prediction of bronchopulmonary dysplasia by identifying kidney-based risk factors

NIH-funded research Indiana University Indianapolis · NIH-10991668

This study is looking at how kidney problems and too much fluid can lead to serious lung issues in premature babies, and it aims to help doctors spot which babies might be at risk so they can provide better care and improve their health.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionIndiana University Indianapolis NIH-funded
Lab location1 site (Indianapolis, United States)
Project IDNIH-10991668 on NIH RePORTER

What this research studies

This research focuses on understanding how acute kidney injury and fluid overload affect the development of severe bronchopulmonary dysplasia (BPD) in premature infants. By identifying kidney-based risk factors, the study aims to create a clinical prediction model that can help healthcare providers identify at-risk infants early on. The approach involves analyzing data from premature infants to establish connections between kidney health and lung disease, ultimately leading to better-targeted interventions. The goal is to improve outcomes for these vulnerable infants by addressing preventable and treatable conditions.

Who could benefit from this research

Good fit: Ideal candidates for this research are premature infants born before 28 weeks of gestation who may be at risk for developing severe bronchopulmonary dysplasia.

Not a fit: Patients who are not premature or do not have risk factors for bronchopulmonary dysplasia may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved early detection and prevention strategies for severe bronchopulmonary dysplasia in premature infants.

How similar studies have performed: Other research has shown promising results in identifying risk factors for bronchopulmonary dysplasia, making this approach both relevant and potentially impactful.

Where this research is happening

Indianapolis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions acute kidney injury
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.