Identifying harmful substances from electronic cigarette use

Identification of Free Radical Induced Biomarkers of Exposure to Electronic Cigarette Aerosol

NIH-funded research Pennsylvania State Univ Hershey Med Ctr · NIH-11061904

This study is looking at how the harmful chemicals in e-cigarette smoke can damage our cells, especially in young people, to help us better understand the risks of using e-cigarettes.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionPennsylvania State Univ Hershey Med Ctr NIH-funded
Lab location1 site (Hershey, United States)
Project IDNIH-11061904 on NIH RePORTER

What this research studies

This research investigates the harmful effects of electronic cigarette (e-cig) aerosol, particularly focusing on free radicals that may cause cellular damage. By using advanced techniques like electron paramagnetic resonance (EPR) spectroscopy, the study aims to identify specific biomarkers that indicate exposure to e-cig aerosols. The research will analyze how these free radicals interact with body tissues and potentially contribute to diseases such as cancer. Ultimately, the goal is to provide a clearer understanding of the risks associated with e-cig use, especially for young users.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who use electronic cigarettes, particularly youths who are at higher risk of exposure.

Not a fit: Patients who do not use electronic cigarettes or are not exposed to e-cig aerosol may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to the development of specific biomarkers that help assess the health risks of e-cigarette use.

How similar studies have performed: While research on e-cigarettes is ongoing, the specific approach of identifying free radical biomarkers is relatively novel and has not been extensively tested.

Where this research is happening

Hershey, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.