Identifying genetic markers for postpartum psychosis
Official title: Epigenetic Biomarkers of Postpartum Psychosis
Funded at University of Virginia · NIH-10722691 · Data updated 2026-11-12
This study is looking at how certain genes might help us understand who is at risk for postpartum psychosis after having a baby, by analyzing blood samples from women who have experienced this condition, with the hope of finding ways to prevent it in the future.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project start | August 2, 2023 |
| Project end | August 1, 2025 |
| Funding year | 2023 |
| Award (this year) | $451,138 |
| NIH project number | 1R21MH134114-01 |
| Project ID | NIH-10722691 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women who have experienced postpartum psychosis or are at risk for this condition following childbirth.
✕Less likely to help
Patients who have not experienced postpartum psychosis or related reproductive mood disorders may not benefit from this research.
What this research studies
This research investigates the role of specific genetic markers in predicting postpartum psychosis, a severe mental health condition that can occur after childbirth. By analyzing blood samples from women diagnosed with postpartum psychosis, the study aims to identify epigenetic biomarkers that may indicate susceptibility to this condition. The researchers will also conduct genome-wide analyses to discover additional biomarkers that could be unique to postpartum psychosis. This approach could lead to better understanding and prevention strategies for affected women.
Why it matters
Potential benefit: If successful, this research could lead to early identification and preventive measures for postpartum psychosis, potentially improving outcomes for new mothers.
How similar studies have gone: Previous research has successfully identified biomarkers for postpartum depression, suggesting that similar approaches may yield valuable insights for postpartum psychosis.
Where this research is happening
-
University of Virginia
Charlottesville, United States Active
Researchers
- Principal investigator: Payne, Jennifer L — University of Virginia
- Study coordinator: Payne, Jennifer L
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.