Identifying genetic markers for postpartum psychosis

Epigenetic Biomarkers of Postpartum Psychosis

['FUNDING_R21'] · UNIVERSITY OF VIRGINIA · NIH-10722691

This study is looking at how certain genes might help us understand who is at risk for postpartum psychosis after having a baby, by analyzing blood samples from women who have experienced this condition, with the hope of finding ways to prevent it in the future.

Quick facts

Phase['FUNDING_R21']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF VIRGINIA (nih funded)
Locations1 site (CHARLOTTESVILLE, UNITED STATES)
Trial IDNIH-10722691 on ClinicalTrials.gov

What this research studies

This research investigates the role of specific genetic markers in predicting postpartum psychosis, a severe mental health condition that can occur after childbirth. By analyzing blood samples from women diagnosed with postpartum psychosis, the study aims to identify epigenetic biomarkers that may indicate susceptibility to this condition. The researchers will also conduct genome-wide analyses to discover additional biomarkers that could be unique to postpartum psychosis. This approach could lead to better understanding and prevention strategies for affected women.

Who could benefit from this research

Good fit: Ideal candidates for this research are women who have experienced postpartum psychosis or are at risk for this condition following childbirth.

Not a fit: Patients who have not experienced postpartum psychosis or related reproductive mood disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to early identification and preventive measures for postpartum psychosis, potentially improving outcomes for new mothers.

How similar studies have performed: Previous research has successfully identified biomarkers for postpartum depression, suggesting that similar approaches may yield valuable insights for postpartum psychosis.

Where this research is happening

CHARLOTTESVILLE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Mental disorders, Mental health disorders, Psychiatric Disease, Psychiatric Disorder, psychological disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.