Identifying genes linked to substance use disorders in adolescents

Using the Genetic Architecture of Substance Use Disorders to Advance Gene Identification and Understanding of Pathways of Risk

['FUNDING_R01'] · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · NIH-10831522

This study is looking at how our genes might influence substance use problems in teens aged 12 to 20, aiming to find out which specific genes are involved and how they interact with life experiences, so we can improve ways to prevent and treat these issues.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorRUTGERS BIOMEDICAL AND HEALTH SCIENCES (nih funded)
Locations1 site (Newark, UNITED STATES)
Trial IDNIH-10831522 on ClinicalTrials.gov

What this research studies

This research investigates the genetic factors that contribute to substance use disorders, particularly focusing on adolescents aged 12 to 20. By employing advanced multivariate genomic techniques, the project aims to discover specific genes associated with these disorders and understand how these genetic variants interact with environmental factors over time. The study will analyze diverse longitudinal samples to characterize the risk associated with these genetic variants and their impact on mental health. Ultimately, the goal is to enhance prevention, intervention, and treatment strategies for substance use disorders through personalized medicine.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents aged 12 to 20 who are at risk for or currently experiencing substance use disorders.

Not a fit: Patients outside the age range of 12 to 20 or those without substance use disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for adolescents struggling with substance use disorders.

How similar studies have performed: Previous research has shown promising results in identifying genetic factors related to substance use disorders, indicating that this approach has potential for success.

Where this research is happening

Newark, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: ethanol use disorder, alcohol use disorder, Mental health disorders, Psychiatric Disease, Psychiatric Disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.