Identifying factors that predict respiratory failure in patients with breathing difficulties
Physiologic Predictors of Respiratory Failure in Patients Presenting with Dyspnea
['FUNDING_FELLOWSHIP'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-10843751
This study is looking at how certain body signs can help doctors figure out which patients with breathing difficulties, especially those with COVID-19, might be at risk of serious breathing problems before they need a ventilator, so they can get help sooner.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-10843751 on ClinicalTrials.gov |
What this research studies
This research investigates how various physiological factors can predict the likelihood of respiratory failure in patients experiencing dyspnea, particularly in the context of COVID-19. It focuses on understanding abnormalities in gas exchange and breathing mechanics in patients who are not yet on mechanical ventilation. The study employs noninvasive assessments to evaluate these factors and aims to identify patients at risk of worsening respiratory conditions. By analyzing data from spontaneously breathing individuals, the research seeks to improve early intervention strategies for respiratory distress.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults presenting with dyspnea, especially those at risk of respiratory failure due to conditions like COVID-19.
Not a fit: Patients who are already intubated or mechanically ventilated may not benefit from this research as it focuses on those who are spontaneously breathing.
Why it matters
Potential benefit: If successful, this research could lead to better prediction and management of respiratory failure, potentially saving lives and improving outcomes for patients with breathing difficulties.
How similar studies have performed: Previous studies have shown promising results in predicting respiratory outcomes using similar physiological assessments, indicating a potential for success in this research.
Where this research is happening
LA JOLLA, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN DIEGO — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MCGUIRE, WILLIAM CAMERON — UNIVERSITY OF CALIFORNIA, SAN DIEGO
- Study coordinator: MCGUIRE, WILLIAM CAMERON
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acute Respiratory Distress Syndrome, Adult Respiratory Distress Syndrome