Identifying factors that predict respiratory failure in patients with breathing difficulties
Official title: Physiologic Predictors of Respiratory Failure in Patients Presenting with Dyspnea
Funded at University of California, San Diego · NIH-10843751 · Data updated 2026-11-12
This study is looking at how certain body signs can help doctors figure out which patients with breathing difficulties, especially those with COVID-19, might be at risk of serious breathing problems before they need a ventilator, so they can get help sooner.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $89,488 |
| NIH project number | 5F32HL167551-02 |
| Project ID | NIH-10843751 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adults presenting with dyspnea, especially those at risk of respiratory failure due to conditions like COVID-19.
✕Less likely to help
Patients who are already intubated or mechanically ventilated may not benefit from this research as it focuses on those who are spontaneously breathing.
What this research studies
This research investigates how various physiological factors can predict the likelihood of respiratory failure in patients experiencing dyspnea, particularly in the context of COVID-19. It focuses on understanding abnormalities in gas exchange and breathing mechanics in patients who are not yet on mechanical ventilation. The study employs noninvasive assessments to evaluate these factors and aims to identify patients at risk of worsening respiratory conditions. By analyzing data from spontaneously breathing individuals, the research seeks to improve early intervention strategies for respiratory distress.
Why it matters
Potential benefit: If successful, this research could lead to better prediction and management of respiratory failure, potentially saving lives and improving outcomes for patients with breathing difficulties.
How similar studies have gone: Previous studies have shown promising results in predicting respiratory outcomes using similar physiological assessments, indicating a potential for success in this research.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Mcguire, William Cameron — University of California, San Diego
- Study coordinator: Mcguire, William Cameron
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.