Identifying different types of critical illness in patients with acute respiratory distress syndrome and sepsis

Clinical Implementation of Molecular Phenotypes of Critical Illness

['FUNDING_R01'] · WASHINGTON UNIVERSITY · NIH-11050900

This study is looking at how to better understand and treat serious conditions like acute respiratory distress syndrome and sepsis by using smart technology to sort patients based on their unique symptoms, which could help doctors provide more personalized care right in the hospital.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorWASHINGTON UNIVERSITY (nih funded)
Locations1 site (SAINT LOUIS, UNITED STATES)
Trial IDNIH-11050900 on ClinicalTrials.gov

What this research studies

This research focuses on understanding the different molecular phenotypes of acute respiratory distress syndrome (ARDS) and sepsis, which are serious conditions often seen in critical care. By using advanced machine learning techniques, the study aims to develop a system that can classify patients based on their specific illness characteristics using easily obtainable clinical data like vital signs and lab results. This classification could help tailor treatments more effectively and improve patient outcomes. The goal is to create a tool that can be integrated into electronic health records for real-time use in hospitals.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults diagnosed with acute respiratory distress syndrome or sepsis.

Not a fit: Patients with chronic respiratory conditions or those not experiencing acute respiratory distress may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more personalized and effective treatments for patients suffering from ARDS and sepsis.

How similar studies have performed: Previous research has shown promise in using machine learning for patient classification in critical care, indicating potential for success in this novel approach.

Where this research is happening

SAINT LOUIS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acute Respiratory Distress Syndrome, acute respiratory distress syndrome caused by sepsis, Adult Respiratory Distress Syndrome

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.