Identifying causes and improving treatment for severe fever in African children
Fever Etiology and Prognostic Point-of-Care Biomarkers in African Children with Severe Febrile Illness
This study is looking into why young children in sub-Saharan Africa get very sick with fevers, and it aims to find better ways to quickly identify serious infections so that doctors can provide the right care faster.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10861095 on NIH RePORTER |
What this research studies
This research focuses on understanding the causes of severe febrile illness in children under 12 years old in sub-Saharan Africa. It aims to improve the rapid identification of serious bacterial infections using advanced techniques like next-generation sequencing and point-of-care biomarkers. By collaborating with hospitals in Tanzania and utilizing innovative bioinformatics, the study seeks to develop a treatment algorithm that can guide urgent care for affected children. The research will analyze clinical data and diagnostic methods to enhance patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who present with severe febrile illness in sub-Saharan Africa.
Not a fit: Patients outside the age range of 0-11 years or those not experiencing severe febrile illness may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to faster and more accurate treatments for severe febrile illness in children, potentially reducing mortality rates.
How similar studies have performed: Previous research has shown promise in using advanced sequencing and biomarker approaches for diagnosing infections, indicating potential success for this study.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Kortz, Teresa — University of California, San Francisco
- Study coordinator: Kortz, Teresa
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.