Identifying biomarkers to monitor lupus disease activity
Monitoring Disease in Lupus
This study is looking at certain proteins in your body fluids that could help doctors better diagnose and track Systemic Lupus Erythematosus (SLE), so they can improve treatment and care for people living with lupus.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10976598 on NIH RePORTER |
What this research studies
This research investigates the identification of specific proteins in body fluids that can help diagnose and monitor Systemic Lupus Erythematosus (SLE), an autoimmune disease affecting multiple organ systems. The project aims to validate a set of ten proteins, known as the LN-10-plex, which have shown promise in reflecting disease activity across diverse patient populations. By utilizing advanced proteomic techniques, the study seeks to enhance the understanding of lupus and improve patient outcomes through better monitoring and treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Systemic Lupus Erythematosus, particularly those experiencing varying degrees of disease activity.
Not a fit: Patients with other autoimmune diseases or those not diagnosed with lupus may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate monitoring of lupus disease activity, allowing for timely and personalized treatment adjustments.
How similar studies have performed: Previous research has successfully identified biomarkers in lupus, indicating that this approach has potential for further advancements in disease monitoring.
Where this research is happening
Houston, United States
- University of Houston — Houston, United States (Active)
Researchers
- Principal investigator: Mohan, Chandra — University of Houston
- Study coordinator: Mohan, Chandra
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.