Identifying biomarkers for brain diseases related to small blood vessel issues.
VCID Biomarkers Coordinating Center
This study is looking for signs in the body that can help us understand and track brain health in people with small vessel disease, which can lead to memory problems and dementia, and it's open to individuals from different backgrounds who want to help us learn more over the next three years.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10685010 on NIH RePORTER |
What this research studies
This research focuses on identifying and validating biomarkers associated with cerebral small vessel disease (SVD), which contributes to cognitive impairment and dementia. The project is coordinated from Massachusetts General Hospital and involves multiple medical centers across the U.S. Researchers will enroll individuals who meet specific eligibility criteria and follow them over three years to assess the biomarkers' effectiveness. The goal is to ensure that the findings are applicable to diverse populations, including African American, Hispanic, and Caucasian individuals.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals with varying degrees of cognitive impairment, particularly those from underrepresented populations.
Not a fit: Patients with cognitive impairment not related to small vessel disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnosis and treatment options for patients suffering from cognitive impairment and dementia related to small vessel disease.
How similar studies have performed: Previous research has shown promise in identifying biomarkers for brain diseases, making this approach a continuation of ongoing efforts in the field.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Greenberg, Steven M — Massachusetts General Hospital
- Study coordinator: Greenberg, Steven M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.