IDDRC at CHOP/Penn: Advancing understanding and treatment of intellectual and developmental disabilities
Official title: The Intellectual and Developmental Disabilities Research Center (IDDRC) at CHOP/Penn
Funded at Children's Hosp of Philadelphia · NIH-11520438 · Data updated 2026-11-12
A grant supplement supports CHOP and Penn researchers in continuing a big, collaborative program to study the causes, brain changes, and potential treatments for intellectual and developmental disabilities.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | September 18, 2026 |
| Project end | May 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $1,169,275 |
| NIH project number | 3P50HD105354-05S1 |
| Project ID | NIH-11520438 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals with intellectual and developmental disabilities and their families who may benefit from improved understanding, diagnosis, and potential therapies.
✕Less likely to help
Families seeking short-term or unrelated medical therapies may not directly benefit from this grant.
What this research studies
This supplement keeps a long-running IDD research center active, strengthening cores that use genetics and neuroscience to understand how gene variants affect brain structure and behavior. Researchers work with both human participants and animal models to explore development from early childhood onward. The center aims to translate discoveries into biomarkers and new options for treatment, supported by shared resources and collaboration across career stages. The work combines basic science with translational aims to improve outcomes for individuals with IDDs and their families.
Why it matters
Potential benefit: If successful, the program could lead to earlier diagnosis, better biomarkers, and new strategies to prevent or treat IDDs.
How similar studies have gone: Prior IDDRC-related work has advanced understanding of brain development and IDDs and informed later translational efforts; this supplement builds on that foundation.
Where this research is happening
-
Children's Hosp of Philadelphia
Philadelphia, United States Active
Researchers
- Principal investigator: Schultz, Robert Thomas — Children's Hosp of Philadelphia
- Study coordinator: Schultz, Robert Thomas
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.