NIH-funded research NIH-funded research

I CARE: Understanding skin-related immune side effects from cancer immunotherapy

Official title: Project 2: I CARE (Immunotherapy Cutaneous Adverse events REsearch)

Funded at City College of New York · NIH-11413612 · Data updated 2026-11-12

This program studies immune-related skin side effects from cancer immunotherapy to improve how patients are counseled and cared for.

More Immunotherapy research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionCity College of New York
NIH-funded
Lab location1 site (New York, United States)
Project startSeptember 26, 2008
Project endAugust 31, 2029
Funding year2026
Award (this year)$193,496
NIH project number5U54CA132378-18
Project IDNIH-11413612 on NIH RePORTER

Who could benefit from this research

Could help

Adults undergoing cancer treatment with immune checkpoint inhibitors, especially those with or at risk for cutaneous adverse events and varied socioeconomic backgrounds.

Less likely to help

Patients not experiencing ircAEs or those not receiving ICIs may not benefit directly.

What this research studies

Cancer patients receiving immune checkpoint inhibitors can develop inflammatory skin problems called ircAEs, which can affect quality of life and treatment decisions. The project will examine biological and social factors that influence who is most at risk and who experiences worse outcomes, using skin tissue and other samples. By studying these skin reactions, doctors hope to tailor supportive care and possibly adjust cancer treatment for those at higher risk. The work will build on existing biological samples and data to connect biology with patient experiences across diverse populations.

Why it matters

Potential benefit: Patients could receive more personalized care to prevent or mitigate skin-related side effects and maintain cancer treatment when possible.

How similar studies have gone: Previous research has shown that identifying risk factors can lead to better management of irAEs, though more work is needed for cutaneous irAEs and diverse populations.

Where this research is happening

  • City College of New York
    New York, United States
    Active

Researchers

  • Principal investigator: Vuong, Bao Q — City College of New York
  • Study coordinator: Vuong, Bao Q

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.