How vaping affects lung immunity and infection risk

Vaping has an immunosuppressive effect, rendering the lung more susceptible to microbial infections

NIH-funded research North Carolina Central University · NIH-11190785

This work explores how e-cigarette use might weaken your lungs' defenses, making them more vulnerable to infections.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionNorth Carolina Central University NIH-funded
Lab location1 site (Durham, United States)
Project IDNIH-11190785 on NIH RePORTER

What this research studies

We know that traditional smoking harms the lungs, but less is understood about e-cigarettes. This project aims to understand if exposure to vaped e-liquid makes the lungs more likely to get sick. Researchers will use human lung cells in the lab and animal models to see how vaping affects lung health and immune cells. The goal is to uncover how vaping might start or worsen lung diseases.

Who could benefit from this research

Good fit: This foundational work is relevant to individuals who use e-cigarettes and are concerned about their lung health or susceptibility to infections.

Not a fit: Patients who do not use e-cigarettes or have pre-existing lung conditions unrelated to vaping may not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this work could help us understand the health risks of e-cigarettes and guide public health recommendations for vapers.

How similar studies have performed: While traditional smoking effects are well-documented, research specifically on e-cigarettes and lung immunity is still emerging and actively being explored.

Where this research is happening

Durham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acute Lung InjuryAcute Pulmonary InjuryAirway infections
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.