How treating sleep apnea affects memory and brain health in Black patients
Official title: Treatment of OSA on sleep-dependent memory and blood biomarkers in blacks
Funded at Icahn School of Medicine at Mount Sinai · NIH-10740142 · Data updated 2026-11-12
This study is looking at how customized treatments for sleep apnea can help improve memory and brain health in Black patients, using a mix of therapies that fit each person's needs, along with support and monitoring to make sure they stick with the treatment.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2026 |
| Funding year | 2023 |
| Award (this year) | $2,531,399 |
| NIH project number | 1RF1AG083975-01 |
| Project ID | NIH-10740142 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are Black individuals diagnosed with obstructive sleep apnea who may benefit from personalized treatment approaches.
✕Less likely to help
Patients who do not have obstructive sleep apnea or those who are not Black may not receive benefits from this research.
What this research studies
This research investigates the effects of personalized treatment for obstructive sleep apnea (OSA) on cognitive function and Alzheimer's disease biomarkers in Black patients. The study aims to improve adherence to treatment by offering a combination of therapies, including positive airway pressure (PAP), oral appliances, and positional therapy, tailored to individual needs. Participants will receive personalized education and real-time monitoring to enhance treatment effectiveness. The research will measure changes in memory and blood biomarkers before and after treatment.
Why it matters
Potential benefit: If successful, this research could lead to improved cognitive health and reduced Alzheimer's disease risk for Black patients suffering from sleep apnea.
How similar studies have gone: Previous research has shown promising results in improving cognitive outcomes through effective OSA treatment, but this specific approach targeting Black patients is innovative and less explored.
Where this research is happening
-
Icahn School of Medicine at Mount Sinai
New York, United States Active
Researchers
- Principal investigator: Kam, Korey — Icahn School of Medicine at Mount Sinai
- Study coordinator: Kam, Korey
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.