How treating sleep apnea affects memory and brain health in Black patients

Treatment of OSA on sleep-dependent memory and blood biomarkers in blacks

NIH-funded research Icahn School of Medicine at Mount Sinai · NIH-10740142

This study is looking at how customized treatments for sleep apnea can help improve memory and brain health in Black patients, using a mix of therapies that fit each person's needs, along with support and monitoring to make sure they stick with the treatment.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10740142 on NIH RePORTER

What this research studies

This research investigates the effects of personalized treatment for obstructive sleep apnea (OSA) on cognitive function and Alzheimer's disease biomarkers in Black patients. The study aims to improve adherence to treatment by offering a combination of therapies, including positive airway pressure (PAP), oral appliances, and positional therapy, tailored to individual needs. Participants will receive personalized education and real-time monitoring to enhance treatment effectiveness. The research will measure changes in memory and blood biomarkers before and after treatment.

Who could benefit from this research

Good fit: Ideal candidates for this research are Black individuals diagnosed with obstructive sleep apnea who may benefit from personalized treatment approaches.

Not a fit: Patients who do not have obstructive sleep apnea or those who are not Black may not receive benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved cognitive health and reduced Alzheimer's disease risk for Black patients suffering from sleep apnea.

How similar studies have performed: Previous research has shown promising results in improving cognitive outcomes through effective OSA treatment, but this specific approach targeting Black patients is innovative and less explored.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Sleep Apnea SyndromesSleep-Disordered Breathingsleep-related breathing disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.