NIH-funded research R01 grant

How toddlers learn and remember words

Official title: Neural Substrates of Word Retention and Generalization in Toddlers

Funded at University of California at Davis · NIH-10903632 · Data updated 2026-11-12

This study is looking at how toddlers aged 2 to 3 years learn and remember new words, using special brain scans to see how their brains help them keep those words in mind, which could help us understand why some kids pick up vocabulary faster than others.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California at Davis
NIH-funded
Lab location1 site (Davis, United States)
Project startSeptember 1, 2024
Project endJuly 31, 2029
Funding year2024
Award (this year)$542,304
NIH project number1R01HD112686-01A1
Project IDNIH-10903632 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are toddlers aged 25 to 35 months, particularly those who may be at risk for language delays or have developmental conditions such as Autism Spectrum Disorder (ASD).

Less likely to help

Patients outside the age range of 25 to 35 months or those with severe cognitive impairments may not benefit from this research.

What this research studies

This research investigates how toddlers aged 2 to 3 years learn and retain new words over time. By using advanced functional Magnetic Resonance Imaging (fMRI) techniques, the study aims to understand the brain processes involved in vocabulary retention and generalization. It focuses on the role of the hippocampus and other brain regions in helping children remember words and their meanings, especially through repeated exposure in their environment. The findings could provide insights into individual differences in vocabulary development among young children.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for enhancing vocabulary development in toddlers, potentially benefiting their academic achievement.

How similar studies have gone: Previous research has successfully utilized fMRI to study language development in older children, but this specific focus on toddlers is relatively novel.

Where this research is happening

  • University of California at Davis
    Davis, United States
    Active

Researchers

  • Principal investigator: Ghetti, Simona — University of California at Davis
  • Study coordinator: Ghetti, Simona

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.