How the immune system affects kidney function and blood pressure in women with autoimmune disease
Innate Immune Mediated Changes in Renal Function to Cause Hypertension in Females with Autoimmune Disease
This study is looking at how the immune system affects kidney health and blood pressure in women with autoimmune diseases like lupus, to find new ways to help manage high blood pressure in these patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Augusta University NIH-funded |
| Lab location | 1 site (Augusta, United States) |
| Project ID | NIH-10918132 on NIH RePORTER |
What this research studies
This research investigates the relationship between the immune system and kidney function in women suffering from autoimmune diseases, particularly systemic lupus erythematosus (SLE). It aims to understand how immune responses contribute to hypertension by examining the mechanisms that lead to kidney damage and increased blood pressure. The study will utilize experimental models to explore how certain immune cells and signals affect kidney health and function. By identifying these pathways, the research hopes to uncover potential therapeutic targets for managing hypertension in affected patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are women diagnosed with systemic lupus erythematosus or other autoimmune diseases who are experiencing hypertension.
Not a fit: Patients without autoimmune diseases or those not experiencing hypertension may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for hypertension in women with autoimmune diseases, improving their overall health and quality of life.
How similar studies have performed: Previous research has shown promising results in understanding the immune mechanisms involved in hypertension, suggesting that this approach could yield valuable insights.
Where this research is happening
Augusta, United States
- Augusta University — Augusta, United States (Active)
Researchers
- Principal investigator: Ryan, Michael — Augusta University
- Study coordinator: Ryan, Michael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.