How the cerebellum affects thinking in people with psychosis
Cerebellar Modulation of Cognition in Psychosis
This study is looking at how a part of the brain called the cerebellum affects thinking problems in people with conditions like schizophrenia and bipolar disorder, and it hopes to find ways to improve these thinking skills using safe brain stimulation techniques.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11002325 on NIH RePORTER |
What this research studies
This research investigates the role of the cerebellum in cognitive impairments associated with psychotic disorders like schizophrenia and bipolar disorder. By using advanced neuroimaging techniques and non-invasive neuromodulation methods such as transcranial magnetic stimulation (TMS), the study aims to identify and modify specific brain circuits linked to cognitive function. The goal is to establish a causal relationship between these circuits and cognitive changes, ultimately leading to targeted interventions for cognitive deficits in affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with schizophrenia, bipolar disorder, or related psychotic disorders who experience significant cognitive impairments.
Not a fit: Patients without a diagnosis of psychotic disorders or those who do not experience cognitive deficits may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve cognitive function and quality of life for patients with psychotic disorders.
How similar studies have performed: Previous research has shown promising results in using neuromodulation techniques to influence brain circuits, indicating potential for success in this novel approach.
Where this research is happening
Boston, United States
- Beth Israel Deaconess Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Brady, Roscoe O. — Beth Israel Deaconess Medical Center
- Study coordinator: Brady, Roscoe O.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.