How the brain processes sensations during different states of wakefulness and sleep in early development

State-dependent sensory processing across early development

NIH-funded research University of Iowa · NIH-10656357

This study looks at how young animals, like babies, tell the difference between what they feel from their own movements and what they feel from the outside world, and it explores how sleep affects this ability to understand sensations as their brains grow and develop.

Quick facts

Grant typeR37 grant
Study typeNIH-funded research
Funding institutionUniversity of Iowa NIH-funded
Lab location1 site (Iowa City, United States)
Project IDNIH-10656357 on NIH RePORTER

What this research studies

This research investigates how young animals, including infants, distinguish between sensations they produce themselves and those from external sources. It focuses on the role of corollary discharge, a mechanism that helps the brain prepare for incoming sensory information based on self-generated movements. By studying these processes in early infancy and how they are influenced by sleep-wake states, the research aims to uncover important insights into sensory processing and brain development. The study uses animal models to observe neural activity patterns during different states, providing a deeper understanding of sensory integration in the developing brain.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research include infants and young children experiencing sensory processing challenges.

Not a fit: Patients with fully developed sensory processing systems or those outside the age range of 0-21 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment of sensory processing disorders in children and adults.

How similar studies have performed: While the specific focus on state-dependent sensory processing in early development is novel, related research has shown success in understanding sensory integration mechanisms in other contexts.

Where this research is happening

Iowa City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Mental disordersMental health disordersPsychiatric DiseasePsychiatric Disorderpsychological disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.