How the brain organizes and retrieves memories over time
Official title: Reorganization of cortical memory ensembles across time
Funded at University of California Los Angeles · NIH-10873018 · Data updated 2026-11-12
This study looks at how our brains remember and recall experiences, especially scary ones, and how this changes as time goes by, so we can better understand how memories work and affect our behavior.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | June 1, 2023 |
| Project end | January 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $78,892 |
| NIH project number | 5F32MH133387-02 |
| Project ID | NIH-10873018 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research would include individuals experiencing anxiety disorders or those interested in understanding memory processes.
✕Less likely to help
Patients with no history of anxiety disorders or memory issues may not receive direct benefits from this research.
What this research studies
This research investigates how the brain encodes, retains, and retrieves memories of experiences, particularly focusing on how these processes change over time. It examines the neural circuits involved in recalling fearful memories, comparing recent and remote retrievals to understand the dynamic nature of memory organization. By studying specific brain regions, particularly the medial prefrontal cortex, the research aims to uncover how different neural activities contribute to memory retrieval across various timeframes. This could provide insights into the underlying mechanisms of memory and its impact on behavior.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment of anxiety disorders and memory-related conditions.
How similar studies have gone: Previous research has shown promising results in understanding memory dynamics, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Zeidler, Zachary E — University of California Los Angeles
- Study coordinator: Zeidler, Zachary E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.