How the brain controls kidney function
Autonomic control of kidney function
['FUNDING_R01'] · BETH ISRAEL DEACONESS MEDICAL CENTER · NIH-11092691
This study is looking at how certain brain cells help control kidney function, especially when the kidneys are injured, to find new ways to improve kidney health.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BETH ISRAEL DEACONESS MEDICAL CENTER (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11092691 on ClinicalTrials.gov |
What this research studies
This research investigates how specific brain neurons regulate kidney function, particularly during acute kidney injury. By examining the connections between the hypothalamus and spinal cord, researchers aim to understand how these neurons influence kidney processes such as salt balance and blood flow. The study employs advanced techniques like RNA sequencing to identify and characterize the neuron populations involved in renal control. This could lead to new insights into managing kidney-related health issues.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing acute kidney injury or those at risk for kidney-related complications.
Not a fit: Patients with chronic kidney disease unrelated to acute injury may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for acute kidney injury and related conditions.
How similar studies have performed: Other research has shown promising results in understanding brain-kidney interactions, suggesting potential for breakthroughs in this area.
Where this research is happening
BOSTON, UNITED STATES
- BETH ISRAEL DEACONESS MEDICAL CENTER — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZEIDEL, MARK L. — BETH ISRAEL DEACONESS MEDICAL CENTER
- Study coordinator: ZEIDEL, MARK L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: acute kidney injury, Aujeszky's Disease Virus, Aujeszkys Disease Virus