NIH-funded research R21 grant

How synthetic sex hormones affect methamphetamine use in women

Official title: Influence of synthetic sex hormones on methamphetamine effects and self-administration in women

Funded at University of Illinois at Chicago · NIH-10837084 · Data updated 2026-11-12

This study is looking at how synthetic hormones, like those in birth control, might affect how women use and feel about methamphetamine, with the goal of finding better treatment options for women dealing with addiction.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Illinois at Chicago
NIH-funded
Lab location1 site (Chicago, UNITED STATES)
Project startMay 15, 2023
Project endApril 30, 2026
Funding year2024
Award (this year)$199,875
NIH project number5R21DA057071-02
Project IDNIH-10837084 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are women who are experiencing methamphetamine use disorder or are at risk of developing it.

Less likely to help

Patients who are not women or those who do not use methamphetamine may not benefit from this research.

What this research studies

This research investigates the impact of synthetic sex hormones on the effects and self-administration of methamphetamine in women. It aims to understand the sex differences in methamphetamine use disorder, particularly how hormonal fluctuations influence addiction behaviors. By examining the role of synthetic ovarian hormones, such as progestins found in contraceptives, the study seeks to identify potential treatment strategies tailored for women. The findings could help improve public health approaches for women struggling with methamphetamine use.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for women with methamphetamine use disorder.

How similar studies have gone: While there have been studies on hormonal influences in addiction, the specific focus on synthetic ovarian hormones in relation to methamphetamine use is relatively novel.

Where this research is happening

  • University of Illinois at Chicago
    Chicago, United States
    Active

Researchers

  • Principal investigator: Childs, Emma — University of Illinois at Chicago
  • Study coordinator: Childs, Emma

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.