How specific brain pathways affect emotional memory and protein synthesis
Prefrontal pathway-specific modulation of protein synthesis in emotional memories
This study is looking at how specific brain pathways help us remember emotional experiences, especially when we feel threatened, and it aims to find new ways to help people with conditions like PTSD by understanding how these memories are formed and kept.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University New York Stony Brook NIH-funded |
| Lab location | 1 site (Stony Brook, United States) |
| Project ID | NIH-10997369 on NIH RePORTER |
What this research studies
This research investigates how certain brain pathways influence the formation and consolidation of emotional memories, particularly in response to threats. By studying the mechanisms of protein synthesis in these pathways, the research aims to uncover how emotional memories are formed and maintained. The approach involves using animal models to simulate conditions similar to post-traumatic stress disorder (PTSD), focusing on how different intensities of threats and the ability to control these threats affect memory processes. The findings could lead to targeted therapies for individuals struggling with emotional memory disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who have experienced trauma and may be suffering from PTSD or related emotional memory issues.
Not a fit: Patients who do not have a history of trauma or emotional memory disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide new therapeutic strategies for patients with PTSD and other emotional memory disorders.
How similar studies have performed: Previous research has shown promising results in understanding the neurobiological mechanisms of emotional memory, suggesting that this approach could yield valuable insights.
Where this research is happening
Stony Brook, United States
- State University New York Stony Brook — Stony Brook, United States (Active)
Researchers
- Principal investigator: Shrestha, Prerana — State University New York Stony Brook
- Study coordinator: Shrestha, Prerana
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.