NIH-funded research R15 grant

How social status affects brain health and stress levels

Official title: Social regulation of oxidative stress in the brain

Funded at Central Michigan University · NIH-10730899 · Data updated 2026-11-12

This study looks at how being popular or not among friends affects brain health in cichlid fish, which might help us understand how social stress can impact mental health in people.

More Oxidative Stress research and trials

Quick facts

Grant typeR15 grant
Study typeNIH-funded research
Funding institutionCentral Michigan University
NIH-funded
Lab location1 site (Mount Pleasant, United States)
Project startSeptember 1, 2023
Project endAugust 31, 2026
Funding year2023
Award (this year)$443,315
NIH project number1R15GM150286-01A1
Project IDNIH-10730899 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals experiencing stress-related mental health disorders or those interested in the biological impacts of social environments on mental health.

Less likely to help

Patients with stable mental health and no history of stress-related disorders may not benefit from this research.

What this research studies

This research investigates how social status influences oxidative stress in the brain, which is linked to various mental health conditions. By studying the social behaviors of cichlid fish, the researchers aim to understand the relationship between social stress and brain health. They will explore how both high and low social status can lead to oxidative stress through hormonal changes, particularly focusing on androgens. The findings could provide insights into the biological mechanisms underlying mental health disorders.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for managing stress-related mental health issues.

How similar studies have gone: Other research has shown promising results in understanding the effects of social stress on health, but this specific approach using cichlid fish is relatively novel.

Where this research is happening

  • Central Michigan University
    Mount Pleasant, United States
    Active

Researchers

  • Principal investigator: Dijkstra, Peter Douwe — Central Michigan University
  • Study coordinator: Dijkstra, Peter Douwe

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.