How serotonin affects brain communication related to emotions and thinking
Serotonergic modulation of nucleus reuniens in affective and cognitive behaviors
['FUNDING_R21'] · FLORIDA ATLANTIC UNIVERSITY · NIH-10303284
This study is looking at how serotonin in a specific part of the brain affects feelings, memory, and decision-making, which could help us understand better ways to support mental health and improve thinking skills.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | FLORIDA ATLANTIC UNIVERSITY (nih funded) |
| Locations | 1 site (BOCA RATON, UNITED STATES) |
| Trial ID | NIH-10303284 on ClinicalTrials.gov |
What this research studies
This research investigates the role of serotonin in the nucleus reuniens, a brain region that connects areas involved in emotions and memory. By using pharmacological and genetic techniques, the study aims to understand how serotonin influences behaviors related to anxiety, memory, and decision-making. Patients may benefit from insights gained about how serotonin modulation can affect mental health and cognitive functions. The research employs various behavioral tests in animal models to explore these effects.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing anxiety, depression, or cognitive impairments.
Not a fit: Patients with conditions unrelated to serotonin modulation or those not experiencing mental health issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for anxiety and cognitive disorders by targeting serotonin pathways in the brain.
How similar studies have performed: Previous research has shown promising results in understanding serotonin's role in brain function, suggesting that this approach could yield valuable insights.
Where this research is happening
BOCA RATON, UNITED STATES
- FLORIDA ATLANTIC UNIVERSITY — BOCA RATON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: VERTES, ROBERT PAUL — FLORIDA ATLANTIC UNIVERSITY
- Study coordinator: VERTES, ROBERT PAUL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Mental disorders, Mental health disorders, Psychiatric Disease, Psychiatric Disorder