How seasonal changes affect brain neuron flexibility

Integration of seasonal cues to modulate neuronal plasticity

NIH-funded research University of California at Davis · NIH-10877004

This study looks at how changes in seasons, like longer days and warmer temperatures, affect the brain's ability to adapt and change, especially in areas that control daily habits and mood, and it’s designed to help us understand how these seasonal shifts can influence behavior and brain connections.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of California at Davis NIH-funded
Lab location1 site (Davis, United States)
Project IDNIH-10877004 on NIH RePORTER

What this research studies

This research investigates how seasonal cues, such as changes in day length and temperature, influence the brain's neuronal plasticity, particularly in areas that regulate daily rhythms and dopamine levels. By studying animal models, the research aims to uncover the structural and functional changes in neurons that occur in response to these seasonal cues. The project will explore how these changes affect behavior and brain connectivity, providing insights into the mechanisms behind seasonal adaptations.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research would include individuals experiencing mood disorders that may be influenced by seasonal changes.

Not a fit: Patients with stable mood disorders not affected by seasonal variations may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new understanding of how seasonal changes impact mental health and behavior, potentially informing treatments for mood disorders.

How similar studies have performed: While the integration of seasonal cues and neuronal plasticity is a relatively novel area of research, preliminary studies have shown promising results in understanding how environmental factors influence brain function.

Where this research is happening

Davis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.