How past experiences influence sensory processing in the brain
Official title: Cell type-specific mechanisms of history-dependent perceptual biases in sensory cortex
Funded at University of California Berkeley · NIH-10898898 · Data updated 2026-11-12
This study is looking at how the brain of mice uses past experiences and what they expect to help them understand their senses better, which could give us insights into how our own brains work when we experience different things.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Berkeley NIH-funded |
| Lab location | 1 site (Berkeley, United States) |
| Project start | August 15, 2023 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $111,698 |
| NIH project number | 5K99NS129753-02 |
| Project ID | NIH-10898898 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with sensory processing disorders, such as those with ADHD or autism spectrum disorders.
✕Less likely to help
Patients without sensory processing issues or those not affected by conditions related to sensory perception may not benefit from this research.
What this research studies
This research investigates how the brain's sensory cortex processes information based on past experiences and expectations. By studying mice, the researchers will explore how specific types of brain cells contribute to changes in sensory perception influenced by recent stimuli and rewards. The approach includes behavioral modeling and advanced techniques to observe and manipulate brain activity during goal-directed tasks. This could help us understand the underlying mechanisms of sensory processing and how they relate to behaviors in different contexts.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment of sensory processing disorders in humans.
How similar studies have gone: Previous research has shown promising results in understanding sensory processing through similar experimental approaches, indicating potential for success in this area.
Where this research is happening
-
University of California Berkeley
Berkeley, United States Active
Researchers
- Principal investigator: Ramamurthy, Deepa L — University of California Berkeley
- Study coordinator: Ramamurthy, Deepa L
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.