SCAN: Standardized brain imaging for Alzheimer’s and related dementias
Official title: SCAN: Standardized, Centralized Alzheimer's and Related Dementias Neuroimaging
Funded at University of California Berkeley · NIH-11617743 · Data updated 2026-11-12
A nationwide effort to standardize brain imaging data in people with Alzheimer’s and related dementias so researchers can compare results and learn how to diagnose and track the disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Berkeley NIH-funded |
| Lab location | 1 site (Berkeley, United States) |
| Project start | September 16, 2026 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $4,971,911 |
| NIH project number | 1R56AG104639-01 |
| Project ID | NIH-11617743 on NIH RePORTER |
Who could benefit from this research
✓Could help
Participants with or suspected of Alzheimer’s disease or related dementias who contribute imaging data as part of ADRC activities.
✕Less likely to help
Direct clinical benefits to individuals are not guaranteed during this project; it focuses on data standardization and methodological advances.
What this research studies
This project harmonizes PET and MRI imaging methods across centers to create a unified database of ATN biomarkers (amyloid, tau, neurodegeneration). By standardizing acquisition, quality control, and data curation, it enables reliable comparisons and more powerful analyses across large groups of participants. The work builds on decades of imaging research and aims to support future trials and diagnostic criteria with consistent, high-quality imaging data. Patients may indirectly benefit as methods mature for earlier and more accurate diagnosis and monitoring of disease progression. The project emphasizes collaboration across ADRCs to pool data and accelerate discoveries that could impact care.
Why it matters
Potential benefit: Improved, standardized imaging tools that could enhance diagnosis and monitoring of Alzheimer’s and related dementias.
How similar studies have gone: Previous imaging standardization efforts have enabled large-scale analyses; SCAN2 aims to extend this to even larger, harmonized datasets.
Where this research is happening
-
University of California Berkeley
Berkeley, United States Active
Researchers
- Principal investigator: Jagust, William J. — University of California Berkeley
- Study coordinator: Jagust, William J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.