How our brains categorize new experiences in health and illness

Conte Center: Understanding Latent Cause Inference in Health and Illness

['FUNDING_OTHER'] · PRINCETON UNIVERSITY · NIH-11167606

This work explores how our brains decide if a new situation is familiar or completely new, and how this process might affect mental health conditions like anxiety.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorPRINCETON UNIVERSITY (nih funded)
Locations1 site (Princeton, UNITED STATES)
Trial IDNIH-11167606 on ClinicalTrials.gov

What this research studies

Our brains constantly sort new information, deciding if it fits with what we already know or if it's something entirely new. This sorting process, called latent cause inference, helps us learn and make decisions every day. When this process doesn't work quite right, it might contribute to various mental health challenges. This project uses advanced computer models to understand how people differ in this brain function, how it changes in conditions like anxiety, and which brain areas are involved.

Who could benefit from this research

Good fit: This work is looking for people who experience mental health symptoms, including anxiety, to help understand how their brains process new information.

Not a fit: Patients whose conditions are unrelated to how the brain categorizes new experiences may not directly benefit from this specific line of inquiry.

Why it matters

Potential benefit: Understanding this fundamental brain process could lead to new ways to identify and help people with a wide range of mental health conditions.

How similar studies have performed: This project proposes a novel approach by investigating latent cause inference as a new transdiagnostic domain for mental health, building on existing computational psychiatry methods.

Where this research is happening

Princeton, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Anxiety Disorders

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.