How obesity affects lung injury during acute respiratory distress

Impact of Diet Induced Obesity on Acute Lung Injury

NIH-funded research Weill Medical Coll of Cornell Univ · NIH-11003336

This study is looking at how being overweight might make lung injuries, like those seen in acute respiratory distress syndrome (ARDS), worse, and it aims to find out how certain fats in our diet affect lung health during these injuries, which could help improve treatments for people who are struggling with this condition.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionWeill Medical Coll of Cornell Univ NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11003336 on NIH RePORTER

What this research studies

This research investigates the relationship between diet-induced obesity and the severity of acute lung injury, particularly in the context of acute respiratory distress syndrome (ARDS). By studying animal models, the researchers aim to uncover the biological mechanisms that make obese individuals more susceptible to ARDS. The study focuses on the role of fatty acids and their metabolism in the lungs during episodes of acute injury, which could lead to better understanding and treatment options for affected patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults over 21 years old who are obese and at risk for acute respiratory distress syndrome.

Not a fit: Patients who are not obese or do not have a risk of acute lung injury may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies for obese patients suffering from acute lung injuries.

How similar studies have performed: Previous research has indicated that obesity can worsen outcomes in acute lung injury, suggesting that this study builds on established findings rather than exploring a completely novel approach.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acute Lung InjuryAcute Pulmonary InjuryAcute Respiratory Distress Syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.