NIH-funded research R01 grant

How mouth cooling and flavor taste influence eating behavior

Official title: Temperature and thermogustatory preferences

Funded at University of Oklahoma · NIH-11361127 · Data updated 2026-11-12

This project studies how temperature sensations in the mouth affect why people choose certain foods and flavors.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Oklahoma
NIH-funded
Lab location1 site (Norman, United States)
Project startJuly 3, 2023
Project endJune 30, 2029
Funding year2026
Award (this year)$235,352
NIH project number5R01DC020843-04
Project IDNIH-11361127 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates include individuals concerned with appetite, flavor perception, or eating behaviors who may benefit from insights into how temperature contributes to flavor and intake preferences.

Less likely to help

People with no interest in how mouth temperature influences flavor perception or those not involved in eating or appetite studies may not directly benefit.

What this research studies

Researchers are exploring how thermal sensations in the mouth, especially cooling, influence food preferences and mouthfeel using a mouse model. They have created a specialized device that can vary the temperature of drinks given to mice to see how temperature changes affect licking behavior and flavor perception. The study focuses on a cold-sensing receptor (TRPM8) to understand its role in shaping innate and learned responses to cooled liquids. Findings could illuminate how temperature interacts with taste and flavor to influence eating and drinking choices.

Why it matters

Potential benefit: If successful, the work could lead to better understanding of how temperature affects flavor and eating behaviors, potentially informing treatments for appetite and eating disorders in humans.

How similar studies have gone: Previous studies have shown that temperature and taste can interact to influence licking and intake behaviors in animal models, supporting the viability of this approach.

Where this research is happening

  • University of Oklahoma
    Norman, United States
    Active

Researchers

  • Principal investigator: Lemon, Christian H — University of Oklahoma
  • Study coordinator: Lemon, Christian H

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.