How historic redlining and neighborhood conditions affect health in middle age

The impact of redlining and place-based factors on health at mid-life

NIH-funded research University of Michigan at Ann Arbor · NIH-11257300

This project links past housing discrimination and current neighborhood conditions to chronic and heart health for people in mid-life.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-11257300 on NIH RePORTER

What this research studies

The team is building a national database combining historical redlining maps, environmental hazard records, housing investment and gentrification measures, and long-term neighborhood demographics. They will connect those place-based data to health and mortality records to see how exposures like pollution or limited healthcare access relate to mid-life chronic and cardiovascular illness. Analyses will trace pathways from decades-old housing policies to present-day differences in illness and life expectancy across U.S. communities. Findings are meant to point to neighborhood-level policies or investments that could improve health for people in middle age.

Who could benefit from this research

Good fit: Adults in mid-life (roughly ages 40–64) living in U.S. neighborhoods with varied histories of redlining are the primary population this research addresses.

Not a fit: People outside the mid-life age range or those living outside the United States are less likely to receive direct benefit from this specific project.

Why it matters

Potential benefit: If successful, the work could reveal neighborhood causes of mid-life chronic and heart disease and guide policies or investments to reduce health disparities.

How similar studies have performed: Prior studies have linked historic redlining to shorter life expectancy and higher chronic disease rates, but the detailed causal pathways remain under-studied.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cardiovascular DiseasesChronic Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.