How H. pylori infection affects ribosomal proteins in the body
Redox Regulation of Host Ribosomal Proteins during Helicobacter pylori infection
This study is looking at how an infection with Helicobacter pylori affects certain proteins in your body, which could help us understand more about the health problems linked to this infection.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10823409 on NIH RePORTER |
What this research studies
This research investigates the impact of Helicobacter pylori infection on ribosomal proteins in the human body. It focuses on understanding how the infection leads to the production of reactive oxygen species, which can modify proteins and affect their function. The study will specifically examine two ribosomal proteins, uL14 and eS27, to see how their activity changes during infection. By analyzing these changes, the research aims to uncover new insights into the mechanisms of H. pylori-related diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with H. pylori infection or related gastric conditions.
Not a fit: Patients without H. pylori infection or those with unrelated gastric issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for treating gastric diseases associated with H. pylori infection.
How similar studies have performed: Previous research has shown that understanding the role of reactive oxygen species in infections can lead to significant advancements in treatment strategies, suggesting this approach has potential for success.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Ramanathan, Renuka Ganesh — Yale University
- Study coordinator: Ramanathan, Renuka Ganesh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.