How gut bacteria affect kidney disease progression
Interspecies microbial interactions in CKD
This study is looking at how the bacteria in your gut might affect chronic kidney disease and how certain bacteria could make kidney problems worse, with the hope of finding new ways to help manage the condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project ID | NIH-11083112 on NIH RePORTER |
What this research studies
This research investigates the relationship between gut microbiota and chronic kidney disease (CKD). It aims to understand how changes in gut bacteria contribute to the progression of CKD by producing harmful substances known as uremic toxins. The study will explore the molecular mechanisms behind these interactions, particularly focusing on a specific group of bacteria that may worsen kidney function. By examining these microbial dynamics, the research seeks to uncover potential new therapeutic targets for managing CKD.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who are diagnosed with chronic kidney disease.
Not a fit: Patients with acute kidney injury or those without chronic kidney disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that slow down or prevent the progression of chronic kidney disease.
How similar studies have performed: Previous research has shown promising results in understanding the role of gut microbiota in various diseases, suggesting that this approach could yield valuable insights into CKD.
Where this research is happening
Davis, United States
- University of California at Davis — Davis, United States (Active)
Researchers
- Principal investigator: Baumler, Andreas J — University of California at Davis
- Study coordinator: Baumler, Andreas J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.