How glucose affects skin cell function and health
Official title: GLUCOSE BINDS RBPs TO REGULATE EPIDERMAL HOMEOSTASIS
Funded at Stanford University · NIH-10862163 · Data updated 2026-11-12
This study is looking at how glucose affects certain proteins in skin cells to help them grow and develop properly, which could lead to new ways to understand and treat skin conditions for patients.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | July 1, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $112,798 |
| NIH project number | 1K01AR084077-01 |
| Project ID | NIH-10862163 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from skin diseases or disorders that may be influenced by glucose metabolism.
✕Less likely to help
Patients with skin conditions unrelated to glucose metabolism or those not affected by epidermal differentiation may not benefit from this research.
What this research studies
This research investigates how glucose interacts with specific proteins in skin cells to regulate their growth and differentiation. By using advanced techniques like CRISPR and mass spectrometry, the study aims to identify key RNA-binding proteins that bind glucose and play a crucial role in maintaining healthy skin. The findings could lead to a better understanding of skin diseases and the underlying mechanisms that affect skin health. Patients may benefit from insights into how glucose levels influence skin conditions and potential new treatment strategies.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for various skin diseases by targeting glucose-related pathways.
How similar studies have gone: Other research has shown promising results in understanding the role of glucose in cellular functions, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Miao, Weili — Stanford University
- Study coordinator: Miao, Weili
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.