How genetics influence inflammation after a heart attack
Genetic modulation of inflammation following myocardial infarction
This study is looking at how certain genes might influence the way your body responds to inflammation after a heart attack, especially focusing on special immune cells that help with healing, and we’d love to have patients share their genetic samples to help us learn more about this process.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project ID | NIH-10905830 on NIH RePORTER |
What this research studies
This research investigates how specific genetic factors affect the inflammatory response following a heart attack. It focuses on a type of immune cell, known as regulatory T cells, which play a crucial role in controlling inflammation and promoting healing. By examining genetic variations that influence the activity of these cells, the study aims to understand their impact on heart recovery. Patients may be involved in providing genetic samples to help identify these relationships.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have recently experienced a myocardial infarction and are willing to participate in genetic testing.
Not a fit: Patients who have not had a heart attack or those with pre-existing severe cardiovascular conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for improving heart healing and reducing complications after a heart attack.
How similar studies have performed: Previous research has shown promising results in understanding the role of immune cells in heart healing, suggesting that this approach could yield valuable insights.
Where this research is happening
Columbus, UNITED STATES
- Ohio State University — Columbus, United States (Active)
Researchers
- Principal investigator: Gumina, Richard J — Ohio State University
- Study coordinator: Gumina, Richard J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.